Three or more concussions linked with worse brain function in later life
Three or more concussions linked with worse brain function in later life Experiencing three or more concussions is linked with worsened brain function in later life, according to major new research. The study — the largest of its kind — also found having just one moderate-to-severe concussion, or traumatic brain injury (TBI), can have a […]
New hydrogel stem cell treatment repairs injured brain tissue in mice
New hydrogel stem cell treatment repairs injured brain tissue in mice A new ‘hybrid’ hydrogel, which allows clinicians to safely deliver stem cells to the site of a brain injury in mice, has been developed by researchers from the University of Melbourne and the Australian National University. A hydrogel is a water-based gel that can […]
Distinct brain networks associated with risk and resilience in depression
Distinct brain networks associated with risk and resilience in depression A new study that links the location of brain injury to levels of depression in patients following the injury has identified two distinct brain networks; one associated with increased depression symptoms and one associated with decreased depression symptoms. The large-scale study expands on previous findings […]
Harnessing the immune system to treat traumatic brain injury in mice
Harnessing the immune system to treat traumatic brain injury in mice Researchers have designed a targeted therapeutic treatment that restricts brain inflammation. The effectiveness of this approach in improving outcomes was demonstrated following brain injury, stroke or multiple sclerosis in mice. The system increases the number of regulatory T cells, mediators of the immune system’s […]
Scientists uncover a new role for blood-brain barrier in neuron function and damage
Scientists uncover a new role for blood-brain barrier in neuron function and damage While the role of the blood-brain barrier has long been appreciated for its ability to maintain precise control over what molecules can enter the nervous system, very little is known about how the cells that form the barrier influence the function of […]
Mild traumatic brain injury increases risk of behavioral and emotional problems in kids
Mild traumatic brain injury increases risk of behavioral and emotional problems in kids University of Rochester researchers have been at the forefront of efforts to understand how blows to the head impact the brain, including how concussions change brain structure . Now researchers at the Del Monte Institute for Neuroscience have found that kids who […]
Surprising culprit worsens stroke, TBI damage
Surprising culprit worsens stroke, TBI damage A new study provides for the first time the surprising evidence that four common nonexcitatory amino acids that usually make proteins which are essential to brain function, instead cause irreversible, destructive swelling of both the astrocytes that support neurons and the neurons themselves in the aftermath of stroke, TBI. […]
Neuroscientists create maps of the brain after traumatic brain injury
Neuroscientists create maps of the brain after traumatic brain injury Scientists from the University of California, Irvine have discovered that an injury to one part of the brain changes the connections between nerve cells across the entire brain. The new research was published this week in Nature Communications. Every year in the United States, nearly […]
Investigational drug fosters nerve repair after injury
Investigational drug fosters nerve repair after injury Scientists from the University of Birmingham have shown that a brain-penetrating candidate drug currently in development as a cancer therapy can foster regeneration of damaged nerves after spinal trauma. The research, published today in Clinical and Translational Medicine, used cell and animal models to demonstrate that when taken […]
Research brings hope for spinal cord injury treatment
Research brings hope for spinal cord injury treatment Scientists from the University of Birmingham have shown an existing drug may reduce damage after spinal cord injury, by blocking the inflammatory response in the spinal cord. Their research, published today in Clinical and Translational Medicine, demonstrates that AZD1236, a drug developed by AstraZeneca, can significantly reduce […]